Origin

Developed by the St. Petersburg Institute of Bioregulation and Gerontology as an ovarian-targeted bioregulator. Unlike most peptides in its family, it's been extensively used in veterinary reproduction research as an FSH alternative.

Mechanism

Proposed to act as an FSH analog or potentiator, enhancing follicular development and oocyte maturation.

Research summary

Evidence

Documented in peer-reviewed veterinary literature (dairy cattle, sheep, goats, 2003-2010) for improved follicle emergence and oocyte recovery in assisted reproduction. No human clinical trials for reproductive use turn up in PubMed. Evidence is moderate for veterinary use, essentially absent for human use.

Evidence tier: Approved in Russia; veterinary research applications documented — see the methodology note for how this is assessed.

Citations

Effects of low-dose follicle-stimulating hormone administration on follicular dynamics and preovulatory follicle characteristics in dairy cows during the summer — Friedman et al. 2010

Reported benefits

ovarian follicle stimulation (veterinary evidence)
claimed improved fertility support in humans (unproven)

Dosing protocols reported in the literature & community

These are protocols reported by compounding pharmacies, published trials, or self-experimentation communities — not a prescription. Start low, especially for anything new.

Reported dosing protocols
Route	Reported protocol
Subcutaneous or intramuscular injection	Veterinary applications: 2.2-4.4 mg on specific estrous-cycle days; human protocols not documented in Western literature.

Side effects

minimal reported in animal studies
potential ovarian hyperstimulation (dose-dependent, theoretical in humans)

Safety notes

Community & reddit notes (anecdotal — not clinical evidence)

Little community discussion. Most literature is veterinary and agricultural, not human self-experimentation.