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Reference

Dosing, reconstitution & safety guide

General mechanics that apply across most injectable peptides. Peptide-specific protocols live on each peptide's own page; this page covers the shared basics.

Supplies for subcutaneous injection

  • Insulin syringes with needles — 29–30 gauge, 1 mL (100-unit) barrel, roughly ½ inch needle length is a common combination.
  • Alcohol wipes — sanitize vial seals and injection-site skin before every injection.
  • Bacteriostatic water — the standard diluent for reconstituting freeze-dried peptide powder. Never use tap water or plain store-bought distilled water, which lack the antimicrobial preservative and are not sterile for injection.

Reconstitution math, worked example

Goal: dissolve a known weight of peptide (e.g. 5 mg) in a volume of bacteriostatic water (e.g. 2 mL), then draw the correct syringe-unit volume to deliver your intended dose.

Conversions: 100 units = 1 mL · 1 unit = 0.01 mL · 1 mg = 1,000 mcg

Worked example: a 5 mg vial, reconstituted with 2 mL of bacteriostatic water, gives a concentration of 2,500 mcg/mL, i.e. 25 mcg per syringe unit. To deliver a 250 mcg dose, draw 10 units.

Example dosing chart, 5 mg in 2 mL
Units drawnDose delivered (5 mg / 2 mL)
250 mcg
4100 mcg
6150 mcg
8200 mcg
10250 mcg

For a blend of two peptides in one vial (e.g. Ipamorelin + Mod-GRF), calculate reconstitution volume based on one peptide's target dose — the other is delivered at the same proportional dose per unit, since both were weighed in equally.

Storage

  • Keep lyophilized (powder) peptides in the freezer until ready to reconstitute.
  • Reconstitute only what you plan to use over the following weeks — not the entire stock at once.
  • Keep reconstituted peptides refrigerated (not frozen) and shielded from light; most tolerate a few weeks refrigerated, though stability varies by compound.
  • Avoid repeated freeze-thaw cycles of reconstituted (liquid) peptide.
  • Swab vial seals with alcohol before every draw to reduce contamination risk across a multi-use vial.

General safety framing

Start low. Individual sensitivity varies substantially, and allergic-type reactions are reported anecdotally even to compounds generally considered gentle (e.g. GH secretagogues). Start at the low end of any reported dose range and monitor for flushing, itching, hives, or heart palpitations, which are treated in the community as signals to stop, not to push through.
  • Sourcing matters. Most peptides discussed in this wiki are sold as research chemicals, "not for human consumption," outside any regulatory quality-control framework. Purity, dosing accuracy and even correct identity of the compound in the vial are not guaranteed.
  • Evidence quality varies enormously peptide-to-peptide. Some compounds in this wiki (semaglutide, tirzepatide, tesamorelin, Thymosin Alpha-1) are FDA-approved drugs or have gone through real placebo-controlled human trials. Others (MOTS-c, Humanin, IGF-1 LR3) have essentially no human trial data at all. Check each peptide's own status pill and research-summary section.
  • Talk to a physician, ideally one familiar with peptide therapy, especially before combining multiple compounds, if you have any chronic condition, are on other medications, or have a personal/family history of cancer.