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Clomiphene Citrate

An FDA-approved selective estrogen receptor modulator used to induce ovulation in women with infertility.

Medications & hormones

Research records

Historical source snapshot. Not freshly verified, not a recommendation. Study findings, community accounts and app defaults are not interchangeable.

Publication suitability · 2026-10-15: Historical reference only; not a clinical verification. Clinical, regulatory, efficacy, safety and dose claims are not independently established by this review.

Clomiphene Citrate

An FDA-approved selective estrogen receptor modulator used to induce ovulation in women with infertility.

Evidence category: Regulator / guideline. This describes the source category, not approval or certainty.

Regulatory statement in source: FDA-approved.

Clomiphene citrate is an FDA-approved selective estrogen receptor modulator (SERM) approved on February 1, 1967, for treatment of ovulatory dysfunction in women desiring pregnancy. It induces ovulation in patients with anovulatory or oligo-ovulatory infertility and is commonly used in polycystic ovarian syndrome and other causes of infertility. Six-month live birth rate ranges from 20-40%.

Benefits reported in the imported source

  • Ovulation induction in women with anovulatory or oligo-ovulatory infertility.
  • Widely used for PCOS-related infertility

Risks and limits

  • Ovarian hyperstimulation syndrome
  • Multiple pregnancy risk
  • Visual disturbances
  • Mood changes

Source bottom line: FDA-approved SERM for fertility with documented efficacy and established safety profile when used under medical supervision.

Uncertainty: Reference information only. Not medical advice.

Study protocols — reports, not instructions

Women with anovulatory or oligo-ovulatory infertility

Reported regimen
Oral administration for ovulation induction
Duration
Typical course spans multiple cycles
Reported outcome
Induces ovulation; six-month live birth rates of 20-40% reported
Source
Clomiphene citrate at 50: the dawning of assisted reproduction (availability check 2026-10-15: source not retrieved; HTTP 403)
Claim provenance

evidence.json#/catalog:hormone:clomiphene-citrate/protocols/0

Community and practice descriptions

Accounts of a practice are not evidence of safety or effectiveness. Words such as “standard”, “safe” or “recommended” describe the source account, not verified consensus or this wiki’s advice. Commercial and self-published citations are retained for traceability, not vendor endorsement or independent clinical corroboration.

Pharmacokinetic context

No half-life recorded in this source snapshot. No value has been inferred.

Source references

Snapshot provenance

Source ID: catalog:hormone:clomiphene-citrate. Commit: adc7684614f9439b41d91a3312b62e7982c7e20e. Review state: historical-not-reverified. Authored links are retained separately from the canonical evidence links in the public data. App templates/defaults and rejected drafts are archived, not deployed.

Related entries and components

None listed.