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Trenbolone

A synthetic anabolic steroid with no approved human indication and extensive reports of severe adverse effects.

Medications & hormones

Research records

Historical source snapshot. Not freshly verified, not a recommendation. Study findings, community accounts and app defaults are not interchangeable.

Publication suitability · 2026-10-15: Historical reference only; not a clinical verification. Clinical, regulatory, efficacy, safety and dose claims are not independently established by this review.

Trenbolone

A synthetic anabolic steroid with no approved human indication and extensive reports of severe adverse effects.

Evidence category: Preclinical. This describes the source category, not approval or certainty.

Regulatory statement in source: Not FDA-approved.

Trenbolone is a synthetic nandrolone analogue first synthesized in the 1960s for veterinary use to enhance cattle growth. A human form, Parabolan, was briefly marketed in France starting in 1980 for muscle-wasting conditions but was withdrawn in 1987 due to significant adverse effects. No approved human medical indication exists.

Benefits reported in the imported source

    Risks and limits

    • 90% of users report adverse effects
    • Severe cardiovascular, hepatic, renal toxicity
    • Psychiatric effects including aggression at higher doses
    • Limited controlled human safety data

    Source bottom line: No approved human medical use; only animal studies and anecdotal reports, with documented serious toxicity.

    Uncertainty: Reference information only. Not medical advice.

    Study protocols — reports, not instructions

    No study protocol recorded in this snapshot. This does not establish that no study exists.

    Community and practice descriptions

    Accounts of a practice are not evidence of safety or effectiveness. Words such as “standard”, “safe” or “recommended” describe the source account, not verified consensus or this wiki’s advice. Commercial and self-published citations are retained for traceability, not vendor endorsement or independent clinical corroboration.

    Pharmacokinetic context

    Historical half-life estimate: 72 hours. Ruiz & Strain (eds.), Lowinson and Ruiz's Substance Abuse (2011), p.358 — compiled reference, no human clinical PK trial; a veterinary/livestock compound (as Finaplix) Population/route context and estimates may differ. This is not a schedule or a verified human dosing rule.

    Source references

    Snapshot provenance

    Source ID: catalog:hormone:trenbolone. Commit: adc7684614f9439b41d91a3312b62e7982c7e20e. Review state: historical-not-reverified. Authored links are retained separately from the canonical evidence links in the public data. App templates/defaults and rejected drafts are archived, not deployed.

    Related entries and components

    None listed.