Methenolone (Primobolan)

Research records

Historical source snapshot. Not freshly verified, not a recommendation. Study findings, community accounts and app defaults are not interchangeable.

Publication suitability · 2026-10-15: Historical reference only; not a clinical verification. Clinical, regulatory, efficacy, safety and dose claims are not independently established by this review.

Methenolone (Primobolan)

An anabolic steroid with limited clinical use and documented risks of androgenic and hepatic toxicity.

Evidence category: Preclinical. This describes the source category, not approval or certainty.

Regulatory statement in source: Limited, largely historical approved human use.

Methenolone (Primobolan) is available as oral tablets (17-acetate) and intramuscular injection (17-enanthate). Human metabolism studies after oral administration show parent steroid detection in urine for up to 90 hours. Limited clinical evidence exists; main risks relate to excessive androgens and 17-alpha-alkylated oral steroid hepatotoxicity.

Benefits reported in the imported source

Risks and limits

• Limited approved human use
• Menstrual irregularities and virilization in women
• Impotence and cardiovascular disease in men
• Liver damage with oral formulation
• Psychiatric changes during and after use

Source bottom line: Preclinical evidence with human metabolism data; significant androgenic and hepatic risks limit approved clinical use.

Uncertainty: Reference information only. Not medical advice.

Study protocols — reports, not instructions

No study protocol recorded in this snapshot. This does not establish that no study exists.

Community and practice descriptions

Accounts of a practice are not evidence of safety or effectiveness. Words such as “standard”, “safe” or “recommended” describe the source account, not verified consensus or this wiki’s advice. Commercial and self-published citations are retained for traceability, not vendor endorsement or independent clinical corroboration.

No community description recorded. This entry has no final B-82 outcome record; it is not a researched-empty finding.

Pharmacokinetic context

Historical half-life estimate: 252 hours. Westreich, in Ruiz & Strain, Lowinson and Ruiz's Substance Abuse (2011), p.358 — enanthate ester (Primobolan Depot) Population/route context and estimates may differ. This is not a schedule or a verified human dosing rule.

Source references

• Studies on Anabolic Steroids—Methenolone Acetate Metabolites - PubMed
• Methenolone (PIM 907) - INCHEM