Ketogenic diet
Very low carbohydrate intake, typically under 50 g daily, to sustain nutritional ketosis.
Food & fasting
Research records
Historical source snapshot. Not freshly verified, not a recommendation. Study findings, community accounts and app defaults are not interchangeable.
Publication suitability · 2026-10-15: Historical reference only; not a clinical verification. Clinical, regulatory, efficacy, safety and dose claims are not independently established by this review.
Ketogenic diet
Very low carbohydrate intake, typically under 50 g daily, to sustain nutritional ketosis.
Evidence category: Systematic review. This describes the source category, not approval or certainty.
Regulatory statement in source: Not separately recorded; do not infer approval from the evidence category.
An umbrella review of 17 meta-analyses covering 68 randomised trials graded the evidence on ketogenic diets. High-quality evidence supported lower seizure frequency and lower triglycerides, and also a rise in LDL cholesterol. Most underlying trials were small (median 42 participants) and short (median 13 weeks), so long-term outcomes are unknown. A separate systematic review of mood and anxiety disorders found only 12 low-quality, mostly uncontrolled studies.
Benefits reported in the imported source
- High-quality evidence from an umbrella review: fewer seizures in children with epilepsy.
- High-quality evidence for lower triglycerides.
Risks and limits
- The same high-quality evidence shows LDL cholesterol rises in type 2 diabetes.
- Underlying trials were mostly small and short, so long-term outcomes are unknown.
- For mood and anxiety, only 12 low-quality studies exist; one panic-disorder case worsened.
Source bottom line: Ketogenic diets have strong evidence for fewer seizures and lower triglycerides, alongside higher LDL.
Uncertainty: Reference information only. Not medical advice.
Study protocols — reports, not instructions
68 randomised trials, median 42 participants each
- Reported regimen
- Ketogenic diets; the standard form limits carbohydrate to under 50 g a day or under 10% of energy, other forms to under 10-50 g a day
- Duration
- Median follow-up 13 weeks
- Reported outcome
- High-quality evidence for fewer seizures in children with epilepsy, lower triglycerides, and higher LDL cholesterol at 12 months in type 2 diabetes.
- Source
- Effects of ketogenic diet on health outcomes: an umbrella review of meta-analyses of randomized clinical trials (availability check 2026-10-15: possible access barrier; not independently inspected; HTTP 200)
Claim provenance
evidence.json#/catalog:food-protocol:keto/protocols/0
389 people with mood or anxiety disorders across 12 studies, nine of them case reports
- Reported regimen
- Low-carbohydrate or ketogenic diets ranging from 0 to under 130 g carbohydrate a day; five studies did not report carbohydrate intake
- Duration
- 2 weeks to 3 years
- Reported outcome
- Studies reported mood stabilisation and fewer symptoms, but no high-quality evidence; one panic-disorder case had higher anxiety, and relapse followed stopping.
- Source
- Efficacy of low carbohydrate and ketogenic diets in treating mood and anxiety disorders: systematic review and implications for clinical practice (availability check 2026-10-15: possible access barrier; not independently inspected; HTTP 200)
Claim provenance
evidence.json#/catalog:food-protocol:keto/protocols/1
Community and practice descriptions
Accounts of a practice are not evidence of safety or effectiveness. Words such as “standard”, “safe” or “recommended” describe the source account, not verified consensus or this wiki’s advice. Commercial and self-published citations are retained for traceability, not vendor endorsement or independent clinical corroboration.
Unverified imported account — A Detailed Beginner's Guide to the Ketogenic Diet - Healthline
An imported authored paraphrase, not a quotation or a recommended protocol.
Review: unverified historical account. The imported wording is preserved for attribution; its full clinical, dosing, efficacy or consensus claims have not been independently established. Described practice context only; no clinical benefit or safety outcome is inferred.
Imported wording: A keto diet guide describes the standard version as roughly 70% of energy from fat, 20% from protein and 10% from carbohydrate; it also describes a cyclical variant with five keto days and two higher-carbohydrate days.
A Detailed Beginner's Guide to the Ketogenic Diet - Healthline
Historical research outcome: verified-description · 2026-10-06
Rechecked the previously published description against live source content. The live guide documents both the stated standard macro proportions and a cyclical variant. The description reports those versions, not health outcomes.
- https://www.healthline.com/nutrition/ketogenic-diet-101: verified-description — The live guide documents both the stated standard macro proportions and a cyclical variant. The description reports those versions, not health outcomes.
Pharmacokinetic context
No half-life recorded in this source snapshot. No value has been inferred.
Source references
- Effects of ketogenic diet on health outcomes: an umbrella review of meta-analyses of randomized clinical trials (availability check 2026-10-15: possible access barrier; not independently inspected; HTTP 200)
- Efficacy of low carbohydrate and ketogenic diets in treating mood and anxiety disorders: systematic review and implications for clinical practice (availability check 2026-10-15: possible access barrier; not independently inspected; HTTP 200)
- PubMed: ketogenic diet
Snapshot provenance
Source ID: catalog:food-protocol:keto. Commit: adc7684614f9439b41d91a3312b62e7982c7e20e. Review state: historical-not-reverified. Authored links are retained separately from the canonical evidence links in the public data. App templates/defaults and rejected drafts are archived, not deployed.
Related entries and components
None listed.