18:6 time-restricted eating
Eighteen-hour fast with a six-hour eating window. A tighter variant of 16:8.
Food & fasting
Research records
Historical source snapshot. Not freshly verified, not a recommendation. Study findings, community accounts and app defaults are not interchangeable.
Publication suitability · 2026-10-15: Historical reference only; not a clinical verification. Clinical, regulatory, efficacy, safety and dose claims are not independently established by this review.
18:6 time-restricted eating
Eighteen-hour fast with a six-hour eating window. A tighter variant of 16:8.
Evidence category: Reference only. This describes the source category, not approval or certainty.
Regulatory statement in source: Not separately recorded; do not infer approval from the evidence category.
This is a tighter form of time-restricted eating, with a long fast and a short eating window. A 2025 scoping review of 81 human studies of time-restricted eating reports better body composition, insulin sensitivity, lipids and inflammation, while noting that people often eat less overall at the same time. A randomised trial in people with type 2 diabetes is testing this pattern over a year, but it is a published protocol with no results yet. No linked study reports outcomes for this specific window.
Benefits reported in the imported source
- A review of 81 studies of time-restricted eating reports better body composition and insulin sensitivity.
- The same review reports better lipids and lower inflammation.
Risks and limits
- No linked study reports outcomes for this specific eating window.
- People often ate less overall, so benefits may come from that rather than timing.
- The trial in type 2 diabetes is a published protocol with no results yet.
Source bottom line: Time-restricted eating looks favourable in review, but this tighter window has no results of its own here.
Uncertainty: Reference information only. Not medical advice.
Study protocols — reports, not instructions
adults with overweight or obesity and type 2 diabetes of under 10 years' duration
- Reported regimen
- 18 hours of fasting with a 6-hour eating window between 2 and 8 PM each day, versus standard lifestyle recommendations
- Duration
- 52 weeks
- Reported outcome
- No results reported: this is a published study protocol and the trial is ongoing.
- Source
- Time Restricted EAting for Type 2 diabetes and MEtabolic health: The TEA TIME trial study protocol (Retnakaran et al. 2026)
Claim provenance
evidence.json#/catalog:food-protocol:18-6/protocols/0
81 human studies of time-restricted eating in a scoping review
- Reported regimen
- the review describes protocols such as 16:8 and 14:10 eating windows
- Duration
- not stated
- Reported outcome
- The review reports better body composition, insulin sensitivity, lipids and inflammation, while noting benefits may coincide with eating less overall.
- Source
- Time-Restricted Eating in Metabolic and Clinical Health: a Current Evidence and Mechanistic Insights (Minari 2026)
Claim provenance
evidence.json#/catalog:food-protocol:18-6/protocols/1
Community and practice descriptions
Accounts of a practice are not evidence of safety or effectiveness. Words such as “standard”, “safe” or “recommended” describe the source account, not verified consensus or this wiki’s advice. Commercial and self-published citations are retained for traceability, not vendor endorsement or independent clinical corroboration.
Unverified imported account — What is Intermittent Fasting? (Love Your Heart podcast) - Cleveland Clinic
An imported authored paraphrase, not a quotation or a recommended protocol.
Review: unverified historical account. The imported wording is preserved for attribution; its full clinical, dosing, efficacy or consensus claims have not been independently established. Described practice context only; no clinical benefit or safety outcome is inferred.
Imported wording: A Cleveland Clinic podcast includes an 18-hour daily fast among time-restricted eating patterns, corresponding to a six-hour eating window.
What is Intermittent Fasting? (Love Your Heart podcast) - Cleveland Clinic
Historical research outcome: verified-description · 2026-10-06
An attributed practice description was verified without importing the source's benefit claims, recommendations or assumptions about prevalence.
- https://my.clevelandclinic.org/podcasts/love-your-heart/what-is-intermittent-fasting: verified-description — Independently read the live source and checked this limited, attributed description: A Cleveland Clinic podcast includes an 18-hour daily fast among time-restricted eating patterns, corresponding to a six-hour eating window.
Pharmacokinetic context
No half-life recorded in this source snapshot. No value has been inferred.
Source references
- Time-Restricted Eating in Metabolic and Clinical Health: a Current Evidence and Mechanistic Insights (Minari 2026)
- Time Restricted EAting for Type 2 diabetes and MEtabolic health: The TEA TIME trial study protocol (Retnakaran et al. 2026)
- PubMed: time-restricted eating
Snapshot provenance
Source ID: catalog:food-protocol:18-6. Commit: adc7684614f9439b41d91a3312b62e7982c7e20e. Review state: historical-not-reverified. Authored links are retained separately from the canonical evidence links in the public data. App templates/defaults and rejected drafts are archived, not deployed.
Related entries and components
None listed.